{"id":91926,"date":"2026-04-10T09:10:03","date_gmt":"2026-04-10T14:10:03","guid":{"rendered":"https:\/\/blog.jackjia.com\/?p=91926"},"modified":"2026-04-10T09:10:03","modified_gmt":"2026-04-10T14:10:03","slug":"20160410-%e6%94%bb%e5%85%8b%e6%97%a0%e8%8d%af%e5%8f%af%e6%b2%bb%e7%9a%84%e7%99%8c%e7%97%87%ef%bc%9a%e5%8a%a0%e6%8b%bf%e5%a4%a7%e7%a7%af%e6%9e%81%e6%8e%a8%e5%8a%a8%e9%9d%9e%e5%95%86","status":"publish","type":"post","link":"https:\/\/blog.jackjia.com\/?p=91926","title":{"rendered":"20160410\/\u653b\u514b\u201c\u65e0\u836f\u53ef\u6cbb\u201d\u7684\u764c\u75c7\uff1a\u52a0\u62ff\u5927\u79ef\u6781\u63a8\u52a8\u975e\u5546\u4e1a\u5316CAR-T\u7ec6\u80de\u7597\u6cd5\u8ba9\u66f4\u591a\u60a3\u8005\u53d7\u76ca"},"content":{"rendered":"<p>\u52a0\u62ff\u5927\u661f\u661f\u751f\u6d3b\u6377\u514b\u4f73\/\u66fe\u88ab\u8ba4\u4e3a\u65e0\u6cd5\u6cbb\u6108\u7684\u764c\u75c7\uff0c\u5982\u4eca\u6b63\u8fce\u6765\u65b0\u7684\u6cbb\u7597\u66d9\u5149\u3002\u5176\u4e2d\uff0cCAR-T\u7ec6\u80de\u7597\u6cd5\uff08\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\u7597\u6cd5\uff09\u6210\u4e3a\u6700\u53d7\u5173\u6ce8\u7684\u7a81\u7834\u4e4b\u4e00\u3002<\/p>\n<p>\u8fd9\u79cd\u7597\u6cd5\u901a\u8fc7\u6539\u9020\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7ec6\u80de\uff0c\u4f7f\u5176\u80fd\u591f\u7cbe\u51c6\u8bc6\u522b\u5e76\u653b\u51fb\u764c\u7ec6\u80de\uff0c\u5df2\u7ecf\u5728\u90e8\u5206\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\u6cbb\u7597\u4e2d\u53d6\u5f97\u663e\u8457\u6548\u679c\u3002<\/p>\n<p><a href=\"http:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_1.png\"><img loading=\"lazy\" src=\"http:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_1.png\" alt=\"\" width=\"579\" height=\"435\" class=\"aligncenter size-full wp-image-91927\" srcset=\"https:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_1.png 579w, https:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_1-300x225.png 300w\" sizes=\"(max-width: 579px) 100vw, 579px\" \/><\/a><\/p>\n<p>\u7136\u800c\uff0c\u5728\u52a0\u62ff\u5927\uff0c\u8fd9\u4e00\u7597\u6cd5\u4ecd\u9762\u4e34\u6210\u672c\u9ad8\u3001\u6d41\u7a0b\u590d\u6742\u7b49\u73b0\u5b9e\u969c\u788d\u3002\u4e3a\u89e3\u51b3\u8fd9\u4e9b\u95ee\u9898\uff0c\u52a0\u62ff\u5927\u7684\u9ad8\u6821\u4e0e\u516c\u5171\u7814\u7a76\u673a\u6784\u6b63\u79ef\u6781\u63a8\u52a8\u201c\u975e\u5546\u4e1a\u5316CAR-T\u7597\u6cd5\u201d\uff0c\u5e0c\u671b\u5728\u4fdd\u8bc1\u7597\u6548\u7684\u540c\u65f6\uff0c\u5927\u5e45\u964d\u4f4e\u6210\u672c\u3001\u63d0\u5347\u53ef\u53ca\u6027\u3002<\/p>\n<p><strong>**\u4ec0\u4e48\u662fCAR-T\u7ec6\u80de\u7597\u6cd5\uff1f<\/strong><\/p>\n<p>CAR-T\u7597\u6cd5\u5c5e\u4e8e\u4e00\u79cd\u201c\u4f53\u5916\u81ea\u4f53\u7ec6\u80de\u6cbb\u7597\u201d\uff08ex vivo autologous therapy\uff09\uff0c\u5373\u4f7f\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7ec6\u80de\u8fdb\u884c\u6539\u9020\u548c\u56de\u8f93\u3002<\/p>\n<p>\u5176\u57fa\u672c\u6d41\u7a0b\u5305\u62ec\uff1a<\/p>\n<p>1\u3001\u91c7\u96c6\u7ec6\u80de\uff1a\u901a\u8fc7\u8840\u6db2\u5206\u79bb\u6280\u672f\uff08apheresis\uff09\u63d0\u53d6\u60a3\u8005\u4f53\u5185\u7684T\u6dcb\u5df4\u7ec6\u80de<\/p>\n<p>2\u3001\u57fa\u56e0\u6539\u9020\uff1a\u5229\u7528\u643a\u5e26CAR\u57fa\u56e0\u7684\u75c5\u6bd2\uff0c\u5c06\u201c\u8bc6\u522b\u764c\u7ec6\u80de\u201d\u7684\u80fd\u529b\u690d\u5165T\u7ec6\u80de<\/p>\n<p>3\u3001\u7ec6\u80de\u6269\u589e\uff1a\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u57f9\u517b\u5e76\u6269\u589e\u6539\u9020\u540e\u7684\u7ec6\u80de<\/p>\n<p>4\u3001\u56de\u8f93\u4f53\u5185\uff1a\u5c06\u589e\u5f3a\u540e\u7684T\u7ec6\u80de\u91cd\u65b0\u6ce8\u5165\u60a3\u8005\u4f53\u5185\uff0c\u5bf9\u764c\u7ec6\u80de\u53d1\u8d77\u653b\u51fb<\/p>\n<p><a href=\"http:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_2.png\"><img loading=\"lazy\" src=\"http:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_2.png\" alt=\"\" width=\"576\" height=\"714\" class=\"aligncenter size-large wp-image-91928\" srcset=\"https:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_2.png 576w, https:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_2-242x300.png 242w\" sizes=\"(max-width: 576px) 100vw, 576px\" \/><\/a><\/p>\n<p>\u4e0d\u540c\u7c7b\u578b\u7684CAR\u53d7\u4f53\u53ef\u9488\u5bf9\u4e0d\u540c\u764c\u75c7\uff0c\u4f8b\u5982\uff1a<\/p>\n<p>CD19\u3001CD22\uff1a\u7528\u4e8e\u6cbb\u7597\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624<\/p>\n<p>BCMA\uff1a\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624<\/p>\n<p><strong>**\u5f53\u524d\u56f0\u5883\uff1a\u6602\u8d35\u4e14\u590d\u6742\u7684\u6cbb\u7597\u4f53\u7cfb<\/strong><\/p>\n<p>\u76ee\u524d\uff0c\u52a0\u62ff\u5927\u5df2\u67096\u79cdCAR-T\u7597\u6cd5\u83b7\u6279\u4f7f\u7528\uff0c\u4f46\u5927\u591a\u7531\u5236\u836f\u516c\u53f8\u96c6\u4e2d\u751f\u4ea7\uff0c\u5b58\u5728\u660e\u663e\u95ee\u9898\uff1a<\/p>\n<p>1. \u6cbb\u7597\u5468\u671f\u957f\u3002\u4ece\u7ec6\u80de\u91c7\u96c6\u5230\u56de\u8f93\u901a\u5e38\u9700\u89814\u81f36\u5468\uff0c\u5bf9\u75c5\u60c5\u5371\u91cd\u60a3\u8005\u6765\u8bf4\u53ef\u80fd\u9519\u5931\u6700\u4f73\u65f6\u673a\uff0c\u5f80\u5f80\u9700\u8981\u201c\u8fc7\u6e21\u6cbb\u7597\u201d\u6765\u7ef4\u6301\u75c5\u60c5\u3002<\/p>\n<p>2. \u6210\u672c\u6781\u9ad8\u3002\u5355\u6b21\u6cbb\u7597\u8d39\u7528\u7ea6\u4e3a44\u4e07\u81f363\u4e07\u52a0\u5143\uff0c\u7ed9\u516c\u5171\u533b\u7597\u4f53\u7cfb\u5e26\u6765\u5de8\u5927\u538b\u529b\uff0c\u4e5f\u9650\u5236\u4e86\u60a3\u8005\u83b7\u5f97\u6cbb\u7597\u7684\u673a\u4f1a\u3002<\/p>\n<p>3. \u5730\u57df\u9650\u5236\u660e\u663e\u3002\u8be5\u7597\u6cd5\u4ec5\u5728\u5927\u578b\u533b\u9662\u63d0\u4f9b\uff0c\u504f\u8fdc\u5730\u533a\u60a3\u8005\u96be\u4ee5\u83b7\u5f97\u540c\u7b49\u533b\u7597\u670d\u52a1\uff0c\u5bfc\u81f4\u533b\u7597\u4e0d\u5e73\u7b49\u95ee\u9898\u52a0\u5267\u3002<\/p>\n<p><strong>**\u65b0\u65b9\u5411\uff1a\u52a0\u62ff\u5927\u201c\u5b66\u672f\u578bCAR-T\u7597\u6cd5\u201d\u5d1b\u8d77<\/strong><\/p>\n<p>\u4e3a\u964d\u4f4e\u6210\u672c\u3001\u6269\u5927\u8986\u76d6\uff0c\u52a0\u62ff\u5927\u591a\u4e2a\u79d1\u7814\u673a\u6784\u6b63\u5728\u5f00\u53d1\u975e\u5546\u4e1a\u5316\uff08\u5b66\u672f\u578b\uff09CAR-T\u7597\u6cd5\u3002<\/p>\n<p>\u76ee\u524d\u5df2\u67093\u9879\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u8fdb\u884c\uff0c\u4e3b\u8981\u9488\u5bf9\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\uff0c\u5305\u62ec\uff1a<\/p>\n<p>CLIC-1901\uff08CD19\u9776\u70b9\uff09<\/p>\n<p>ACIT001\/EXC002\uff08CD19\u9776\u70b9\uff09<\/p>\n<p>CLIC-2201\uff08CD22\u9776\u70b9\uff09<\/p>\n<p>\u5176\u4e2d\uff0cCLIC-1901\u9879\u76ee\u5c24\u4e3a\u5178\u578b\uff0c\u6d89\u53ca\u8de8\u57ce\u5e02\u5408\u4f5c\uff1a<\/p>\n<p>\u6e29\u54e5\u534e\uff1a\u75c5\u6bd2\u8f7d\u4f53\u751f\u4ea7\u4e0e\u7ec6\u80de\u5de5\u7a0b<\/p>\n<p>\u6e25\u592a\u534e\uff1a\u75c5\u6bd2\u5236\u5907<\/p>\n<p>\u533b\u9662\uff1a\u5b8c\u6210\u6700\u7ec8\u56de\u8f93\u6cbb\u7597<\/p>\n<p><a href=\"http:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_3.png\"><img loading=\"lazy\" src=\"http:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_3.png\" alt=\"\" width=\"558\" height=\"445\" class=\"aligncenter size-large wp-image-91929\" srcset=\"https:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_3.png 558w, https:\/\/blog.jackjia.com\/wp-content\/uploads\/2026\/04\/car-t_cell_3-300x239.png 300w\" sizes=\"(max-width: 558px) 100vw, 558px\" \/><\/a><\/p>\n<p><strong>**\u4f18\u52bf\u663e\u73b0\uff1a\u66f4\u5feb\u3001\u66f4\u4fbf\u5b9c\u3001\u66f4\u516c\u5e73<\/strong><\/p>\n<p>\u76f8\u6bd4\u5546\u4e1a\u6a21\u5f0f\uff0c\u5b66\u672f\u578bCAR-T\u7597\u6cd5\u5c55\u73b0\u51fa\u591a\u91cd\u4f18\u52bf\uff1a<\/p>\n<p>1. \u6cbb\u7597\u65f6\u95f4\u5927\u5e45\u7f29\u77ed<\/p>\n<p>\u201c\u9759\u8109\u5230\u9759\u8109\u201d\uff08vein-to-vein\uff09\u65f6\u95f4\u4e2d\u4f4d\u6570\u4ec515\u5929\uff0c\u663e\u8457\u5feb\u4e8e\u4f20\u7edf\u6a21\u5f0f\uff0c\u751a\u81f3\u65e0\u9700\u8fc7\u6e21\u6cbb\u7597\u3002<\/p>\n<p>2. \u6210\u672c\u660e\u663e\u964d\u4f4e<\/p>\n<p>ACIT001\/EXC002\uff1a\u9884\u8ba1\u4f4e\u4e8e10\u4e07\u52a0\u5143<\/p>\n<p>\u897f\u73ed\u7259\u6848\u4f8b\uff1a\u7ea614.5\u4e07\u52a0\u5143<\/p>\n<p>\u8fdc\u4f4e\u4e8e\u73b0\u6709\u5546\u4e1a\u7597\u6cd5<\/p>\n<p>3. \u63d0\u5347\u5168\u56fd\u53ef\u53ca\u6027<\/p>\n<p>\u901a\u8fc7\u5206\u5e03\u5f0f\u751f\u4ea7\u6a21\u5f0f\uff0c\u672a\u6765\u6709\u671b\u8986\u76d6\u66f4\u591a\u7701\u4efd\uff0c\u5305\u62ec\uff1a\u4e0d\u5217\u98a0\u54e5\u4f26\u6bd4\u4e9a\u7701\u3001\u5b89\u5927\u7565\u7701\u3001\u66fc\u5c3c\u6258\u5df4\u7701\u3001\u8428\u65af\u5580\u5f7b\u6e29\u7701\u3001\u65b0\u4e0d\u4f26\u745e\u514b\u7701\u548c\u963f\u5c14\u4f2f\u5854\u7701\u3002<\/p>\n<p><strong>**\u7597\u6548\u5982\u4f55\uff1f\u521d\u6b65\u7ed3\u679c\u4ee4\u4eba\u671f\u5f85<\/strong><\/p>\n<p>\u76ee\u524d\u7684\u4e34\u5e8a\u6570\u636e\u8868\u660e\uff1a<\/p>\n<p>CLIC-1901\uff1a\u7597\u6548\u4e0e\u90e8\u5206\u5546\u4e1a\u7597\u6cd5\u76f8\u5f53\uff0c\u751a\u81f3\u66f4\u4f18\uff0c\u4e14\u6bd2\u6027\u53ef\u80fd\u66f4\u4f4e<\/p>\n<p>ACIT001\/EXC002\uff1a\u5b89\u5168\u6027\u548c\u7597\u6548\u4e0e\u73b0\u6709\u7597\u6cd5\u57fa\u672c\u4e00\u81f4<\/p>\n<p>CLIC-2201\uff1a\u4ecd\u5728\u7b49\u5f85\u7ed3\u679c<\/p>\n<p>\u867d\u7136\u6837\u672c\u91cf\u4ecd\u6709\u9650\uff0c\u4f46\u6574\u4f53\u8d8b\u52bf\u79ef\u6781\uff0c\u4e3a\u672a\u6765\u63a8\u5e7f\u63d0\u4f9b\u4e86\u91cd\u8981\u4f9d\u636e\u3002<\/p>\n<p><strong>**\u672a\u6765\u5c55\u671b\uff1a\u8ba9\u5148\u8fdb\u6cbb\u7597\u771f\u6b63\u201c\u89e6\u624b\u53ef\u53ca\u201d<\/strong><\/p>\n<p>CAR-T\u7597\u6cd5\u4ee3\u8868\u4e86\u764c\u75c7\u6cbb\u7597\u7684\u91cd\u8981\u65b9\u5411\uff0c\u800c\u52a0\u62ff\u5927\u6b63\u5728\u63a2\u7d22\u4e00\u6761\u66f4\u5177\u516c\u5e73\u6027\u4e0e\u53ef\u6301\u7eed\u6027\u7684\u8def\u5f84\u2014\u2014\u901a\u8fc7\u672c\u571f\u7814\u53d1\u548c\u5206\u5e03\u5f0f\u751f\u4ea7\uff0c\u8ba9\u8fd9\u4e00\u201c\u9ad8\u7aef\u7597\u6cd5\u201d\u4e0d\u518d\u53ea\u662f\u5c11\u6570\u4eba\u7684\u9009\u62e9\u3002<\/p>\n<p>\u968f\u7740\u4e34\u5e8a\u8bd5\u9a8c\u4e0d\u65ad\u63a8\u8fdb\uff0c\u5b66\u672f\u578bCAR-T\u7597\u6cd5\u6709\u671b\u5728\u672a\u6765\u51e0\u5e74\u8fdb\u5165\u66f4\u5e7f\u6cdb\u5e94\u7528\u9636\u6bb5\uff0c\u771f\u6b63\u5b9e\u73b0\uff1a\u8ba9\u66f4\u591a\u60a3\u8005\u7528\u5f97\u4e0a\u3001\u7528\u5f97\u8d77\u5148\u8fdb\u6cbb\u7597\u3002<\/p>\n<p>\u65b0\u95fb\u6765\u6e90\uff1a<br \/>\nhttps:\/\/theconversation.com\/treating-previously-untreatable-cancers-how-car-t-cell-therapy-could-be-made-accessible-to-more-patients-270937<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u52a0\u62ff\u5927\u661f\u661f\u751f\u6d3b\u6377\u514b\u4f73\/\u66fe\u88ab\u8ba4\u4e3a\u65e0\u6cd5\u6cbb\u6108\u7684\u764c\u75c7\uff0c\u5982\u4eca\u6b63\u8fce\u6765\u65b0\u7684\u6cbb\u7597\u66d9\u5149\u3002\u5176\u4e2d\uff0cCAR-T\u7ec6\u80de\u7597\u6cd5\uff08\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\u7597\u6cd5\uff09\u6210\u4e3a\u6700\u53d7\u5173\u6ce8\u7684\u7a81\u7834\u4e4b\u4e00\u3002 \u8fd9\u79cd\u7597\u6cd5\u901a\u8fc7\u6539\u9020\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7ec6\u80de\uff0c\u4f7f\u5176\u80fd\u591f\u7cbe\u51c6\u8bc6\u522b\u5e76\u653b\u51fb\u764c\u7ec6\u80de\uff0c\u5df2\u7ecf\u5728\u90e8\u5206\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\u6cbb\u7597\u4e2d\u53d6\u5f97\u663e\u8457\u6548\u679c\u3002 \u7136\u800c\uff0c\u5728\u52a0\u62ff\u5927\uff0c\u8fd9\u4e00\u7597\u6cd5\u4ecd\u9762\u4e34\u6210\u672c\u9ad8\u3001\u6d41\u7a0b&#8230;<br \/><a class=\"read-more-button\" href=\"https:\/\/blog.jackjia.com\/?p=91926\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":91928,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts\/91926"}],"collection":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=91926"}],"version-history":[{"count":1,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts\/91926\/revisions"}],"predecessor-version":[{"id":91930,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts\/91926\/revisions\/91930"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/media\/91928"}],"wp:attachment":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=91926"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=91926"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=91926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}