{"id":60418,"date":"2020-12-17T20:57:25","date_gmt":"2020-12-18T01:57:25","guid":{"rendered":"http:\/\/blog.jackjia.com\/?p=60418"},"modified":"2020-12-17T20:57:25","modified_gmt":"2020-12-18T01:57:25","slug":"20201217mrna%e7%96%ab%e8%8b%97%e4%bc%9a%e6%94%b9%e5%8f%98dna%e5%90%97%ef%bc%9f%e5%8a%a0%e6%8b%bf%e5%a4%a7%e5%8c%bb%e5%ad%a6%e4%b8%93%e5%ae%b6%e5%9b%9e%e5%ba%94%e7%96%ab%e8%8b%97%e6%8e%a5%e7%a7%8d","status":"publish","type":"post","link":"https:\/\/blog.jackjia.com\/?p=60418","title":{"rendered":"20201217\/mRNA\u75ab\u82d7\u4f1a\u6539\u53d8DNA\u5417\uff1f\u52a0\u62ff\u5927\u533b\u5b66\u4e13\u5bb6\u56de\u5e94\u75ab\u82d7\u63a5\u79cd"},"content":{"rendered":"

\uff08\u661f\u661f\u751f\u6d3b\u6377\u514b\u4f73\u62a5\u9053\uff09\u968f\u7740\u52a0\u62ff\u5927\u9996\u6279\u8f89\u745eBioNTech\u65b0\u51a0\u75c5\u6bd2\u75ab\u82d7\u7684\u5230\u6765\uff0c\u6709\u5173\u75ab\u82d7\u7684\u8bf8\u591a\u7591\u8651\u9010\u6e10\u6d6e\u4e0a\u53f0\u9762\uff0c\u5982\u63a5\u79cd\u75ab\u82d7\u6709\u4ec0\u4e48\u526f\u4f5c\u7528\uff1fmRNA\u75ab\u82d7\u4f1a\u6539\u53d8DNA\u5417\uff1f\u75ab\u82d7\u7684\u836f\u6548\u5982\u4f55\uff1f\u5bf9\u5b55\u5987\u548c\u513f\u7ae5\u662f\u5426\u5b89\u5168\uff1f\u7b49\u7b49\u3002\u52a0\u62ff\u5927\u591a\u4f4d\u4e13\u5bb6\u901a\u8fc7\u4e0d\u540c\u5a92\u4f53\u56de\u5e94\u4eba\u4eec\u5173\u6ce8\u7684\u70ed\u70b9\uff0c\u4ee5\u4e0b\u662f\u76f8\u5173\u56de\u7b54\u7684\u6c47\u603b\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u95ee\uff1a\u63a5\u79cd\u75ab\u82d7\u540e\u4f1a\u6709\u4ec0\u4e48\u611f\u89c9\uff1f\u6709\u4ec0\u4e48\u526f\u4f5c\u7528\uff1f<\/strong><\/p>\n

\u5b89\u7701\u533b\u5b66\u534f\u4f1a\u4e13\u5bb6\u5c0f\u7ec4\u6210\u5458\u513f\u79d1\u514d\u75ab\u5b66\u5bb6Zainab Abdurrahman\u535a\u58eb\u89e3\u91ca\u8bf4\uff0c\u75ab\u82d7\u4e2d\u542b\u6709\u5f88\u5c11\u7684\u75c5\u539f\u4f53\uff0c\u4f1a\u8bf1\u4f7f\u8eab\u4f53\u8ba4\u4e3a\u81ea\u5df1\u5df2\u88ab\u611f\u67d3\u3002\u5982\u679c\u4f60\u66fe\u771f\u6b63\u9047\u5230\u8fc7\u75c5\u6bd2\uff0c\u5b83\u5c31\u4f1a\u4ea7\u751f\u514d\u75ab\u53cd\u5e94\u3002\u4e8e\u662f\uff0c\u8eab\u4f53\u5c06\u7ecf\u5386\u62b5\u6297\u611f\u67d3\u7684\u81ea\u7136\u6b65\u9aa4\uff0c\u56e0\u6b64\u53ef\u80fd\u4f1a\u611f\u5230\u75be\u75c5\u75c7\u72b6\uff0c\u5305\u62ec\u53d1\u70e7\uff0c\u5c40\u90e8\u75bc\u75db\u548c\u6ce8\u5c04\u90e8\u4f4d\u80bf\u80c0\u4ee5\u53ca\u5168\u8eab\u4e0d\u9002\u3002<\/p>\n

Abdurrahman\u8bf4\uff1a\u201c\u4eba\u4eec\u53ef\u4ee5\u671f\u5f85\u4e0e\u6d41\u611f\u75ab\u82d7\u7684\u611f\u89c9\u76f8\u4f3c\uff0c\u4e0e\u6240\u83b7\u5f97\u7684\u4efb\u4f55\u5176\u4ed6\u75ab\u82d7\u7684\u611f\u89c9\u76f8\u4f3c\u3002\u8fd9\u4e9b\u5b9e\u9645\u4e0a\u53ea\u662f\u514d\u75ab\u7cfb\u7edf\u5de5\u4f5c\u7684\u8ff9\u8c61\u3002\u201d<\/p>\n

\u95ee\uff1a\u8c01\u4e0d\u5e94\u8be5\u63a5\u79cd\u75ab\u82d7\uff1f<\/strong><\/p>\n

Abdurrahman\u6307\u51fa\uff0c\u867d\u7136\u82f1\u56fd\u4e24\u4e2a\u62a4\u58eb\u5728\u6ce8\u5c04\u540e\u51fa\u73b0\u8fc7\u654f\u6837\u75c7\u72b6\u53cd\u5e94\uff0c\u5e76\u5728\u63a5\u53d7\u80be\u4e0a\u817a\u7d20\u540e\u8fc5\u901f\u5eb7\u590d\u3002\u4f46\u6709\u8fc7\u654f\u53cd\u5e94\u7684\u4eba\u5df2\u88ab\u5305\u62ec\u5728\u8bd5\u9a8c\u4e2d\uff0c\u5e76\u4e14\u5bf9\u4e34\u5e8a\u6570\u636e\u7684\u56de\u987e\u663e\u793a\u8fc7\u654f\u53cd\u5e94\u7684\u98ce\u9669\u6ca1\u6709\u589e\u52a0\u3002<\/p>\n

\u5979\u8865\u5145\u8bf4\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40FDA\uff0c\u52a0\u62ff\u5927\u536b\u751f\u90e8\u548c\u52a0\u62ff\u5927\u8fc7\u654f\u4e0e\u4e34\u5e8a\u514d\u75ab\u5b66\u4f1a\u8ba4\u4e3a\uff0c\u552f\u4e00\u5e94\u8be5\u907f\u514d\u4f7f\u7528\u8f89\u745e\u75ab\u82d7\u7684\u4eba\u662f\u90a3\u4e9b\u5bf9\u4e24\u5242\u65b9\u6848\u7684\u7b2c\u4e00\u5242\u8fc7\u654f\u7684\u4eba\uff0c\u6216\u5bf9\u5176\u4e2d\u4e00\u79cd\u6210\u5206\u8fc7\u654f\u7684\u4eba\u3002 <\/p>\n

\u5979\u6307\u51fa\uff0c\u805a\u4e59\u4e8c\u9187\uff08Polyethylene glycol\uff09\u6210\u5206\u4f3c\u4e4e\u4f1a\u5f15\u8d77\u67d0\u4e9b\u53cd\u5e94\uff0c\u4f46\u5979\u8bf4\u8fd9\u662f\u4e00\u79cd\u975e\u5e38\u7f55\u89c1\u7684\u8fc7\u654f\u3002\u201c\u5b9e\u9645\u4e0a\uff0c\u6211\u4eec\u7ecf\u5e38\u4f7f\u7528\u7684\u8bb8\u591a\u836f\u7269\u4e2d\u90fd\u542b\u6709\u805a\u4e59\u4e8c\u9187\uff0c\u5176\u4e2d\u6700\u5e38\u89c1\u7684\u662f\u6cf0\u8bfa\uff08Tylenol\uff09\u3002\u201d<\/p>\n

\u56fd\u5bb6\u514d\u75ab\u54a8\u8be2\u59d4\u5458\u4f1a\u5efa\u8bae\u6000\u5b55\u6216\u6bcd\u4e73\u5582\u517b\u7684\u4eba\u4e5f\u5e94\u907f\u514d\u4f7f\u7528\u75ab\u82d7\u3002<\/p>\n

\u5b89\u7701\u533b\u5b66\u534f\u4f1a\u4e13\u5bb6\u5c0f\u7ec4\u6210\u5458\u3001\u513f\u7ae5\u8fc7\u654f\u75c7\u4e13\u5bb6Mariam Hanna\u535a\u58eb\u8bf4\uff0c\u8fd9\u4e2a\u7ec4\u522b\u7684\u6570\u636e\u4e0d\u8db3\uff0c\u65e0\u6cd5\u77e5\u9053\u4ed6\u4eec\u4f1a\u5982\u4f55\u5e94\u5bf9\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u5979\u4ecd\u5141\u8bb8\u4e00\u4e9b\u4eba\u5728\u4e0e\u533b\u751f\u534f\u5546\u540e\u8003\u8651\u63a5\u79cd\u75ab\u82d7\u3002<\/p>\n

Hanna\u8bf4\uff1a\u201c\u8981\u683c\u5916\u8c28\u614e\uff0c\u4f46\u6211\u4eec\u59cb\u7ec8\u5fc5\u987b\u5728\u98ce\u9669\u4e0e\u6536\u76ca\u4e4b\u95f4\u6743\u8861\uff0c\u5e76\u4e3a\u6b64\u505a\u51fa\u5171\u540c\u7684\u51b3\u5b9a\u3002\u4e86\u89e3\u7684\u4fe1\u606f\u8d8a\u591a\uff0c\u5c31\u8d8a\u5bb9\u6613\u4f7f\u6211\u4eec\u5bf9\u6240\u6709\u5b55\u5987\u548c\u6bcd\u4e73\u5582\u517b\u7684\u5bb6\u5ead\u611f\u5230\u6ee1\u610f\u3002\u201d <\/p>\n

\u95ee\uff1aCOVID-19\u75ab\u82d7\u5b89\u5168\u5417\uff1f<\/strong><\/p>\n

Hanna\u8bf4\uff0c\u75ab\u82d7\u7684\u5b89\u5168\u6027\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u53d7\u5230\u4e86\u4e25\u683c\u7684\u5ba1\u67e5\uff0c\u5f53\u75ab\u82d7\u88ab\u63a8\u5e7f\u5230\u73b0\u5b9e\u4e16\u754c\u65f6\uff0c\u8fd9\u79cd\u5b89\u5168\u6027\u5c06\u7ee7\u7eed\u4e0b\u53bb\u3002\u5c3d\u7ba1\u9884\u671f\u4f1a\u6709\u8f7b\u5fae\u7684\u526f\u4f5c\u7528\uff0c\u4f46\u5730\u65b9\u3001\u7701\u3001\u56fd\u5bb6\u548c\u56fd\u9645\u5c42\u9762\u7684\u4e13\u5bb6\u6b63\u5728\u5bfb\u627e\u53ef\u80fd\u63d0\u793a\u9700\u8981\u8fdb\u4e00\u6b65\u8bc4\u4f30\u7684\u4e0d\u826f\u53cd\u5e94\u3002<\/p>\n

\u201c\u6211\u4eec\u77e5\u9053\u8fd9\u5f88\u5b89\u5168\u3002\u6211\u4eec\u5c06\u7ee7\u7eed\u6536\u96c6\u53ef\u786e\u4fdd\u5176\u5b89\u5168\u6027\u7684\u6570\u636e\u3002\u201dHanna\u8bf4\u3002\u201c\u968f\u7740\u75ab\u82d7\u7684\u63a5\u79cd\uff0c\u73b0\u5b9e\u4e16\u754c\u7684\u6570\u636e\u53ef\u80fd\u662f\u6700\u4ee4\u4eba\u5174\u594b\u7684\u90e8\u5206\uff0c\u56e0\u6b64\uff0c\u5f53\u8f6e\u5230\u4f60\u63a5\u79cd\u75ab\u82d7\u65f6\uff0c\u5b89\u5168\u6027\u6570\u636e\u4e0d\u4ec5\u662f44,000\uff08\u8bd5\u9a8c\uff09\u60a3\u8005\uff0c\u5230\u90a3\u65f6\u7684\u6570\u636e\u5df2\u7ecf\u8fbe\u5230\u4e86\u6570\u767e\u4e07\u3002\u201d<\/p>\n

\"\"<\/a><\/p>\n

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Hanna\u8bf4\uff0c\u76ee\u524d\u7684\u75ab\u82d7\u5df2\u88ab\u6279\u51c6\u7528\u4e8e16\u5c81\u53ca\u4ee5\u4e0a\u7684\u513f\u7ae5\uff0c\u6b63\u5728\u8fdb\u884c\u7684\u8bd5\u9a8c\u9488\u5bf9\u7684\u662f12\u81f315\u5c81\u7684\u513f\u7ae5\u4ee5\u53ca12\u5c81\u4ee5\u4e0b\u7684\u513f\u7ae5\u3002<\/p>\n

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\u201c\u6211\u4eec\u9700\u8981\u5bf9\u513f\u7ae5\u8fdb\u884c\u514d\u75ab\uff0c\u4f46\u9700\u8981\u5b89\u5168\u6027\u6570\u636e\uff0c\u529f\u6548\u6570\u636e\uff0c\u800c\u8fd9\u5373\u5c06\u5230\u6765\u2026\u2026\u6211\u4eec\u9700\u8981\u5728\u6b64\u8fc7\u6e21\u671f\u95f4\u7ee7\u7eed\u4fdd\u6301\u8b66\u60d5\u3002\u7b2c\u4e00\u9636\u6bb5\u63a5\u79cd\u75ab\u82d7\u4e0d\u5305\u62ec\u513f\u7ae5\uff0c\u4e5f\u8bb8\u7b2c\u4e8c\u9636\u6bb5\u4e5f\u4e0d\u5305\u62ec\u513f\u7ae5\uff0c\u4f46\u7b2c\u4e09\u9636\u6bb5\u80af\u5b9a\u4f1a\u5305\u62ec\u513f\u7ae5\u3002\u201d<\/p>\n

\u95ee\uff1a\u5982\u679c\u6709\u8fc7\u654f\u53cd\u5e94\u53ef\u4ee5\u63a5\u79cdCOVID-19\u75ab\u82d7\u5417\uff1f<\/strong><\/p>\n

\u8f89\u745eCOVID-19\u75ab\u82d7\u63a5\u79cd\u8005\u6700\u5e38\u89c1\u7684\u62b1\u6028\u662f\u6ce8\u5c04\u90e8\u4f4d\u4e0d\u8212\u670d\uff0c\u75b2\u52b3\u548c\u5934\u75db\uff0c\u533b\u5b66\u8bd5\u9a8c\u4e2d\u7684\u4e00\u4e9b\u4eba\u62a5\u544a\u8bf4\uff0c\u4ed6\u4eec\u201c\u7b2c\u4e8c\u6b21\u6ce8\u5c04\u540e\u611f\u5230\u6709\u70b9\u75b2\u52b3\u201d\u3002\u52a0\u62ff\u5927\u536b\u751f\u90e8\u9996\u5e2d\u533b\u5b66\u987e\u95eeSupriya Sharma\u535a\u58eb\u5728\u5ba3\u5e03\u8fd9\u6b3e\u75ab\u82d7\u5df2\u83b7\u51c6\u4f7f\u7528\u65f6\u8bf4\uff0c\u8fd9\u4e9b\u53cd\u5e94\u201c\u4e0e\u5176\u4ed6\u75ab\u82d7\u4e00\u6837\u201d\u3002<\/p>\n

\u4e0d\u8fc7\uff0c\u968f\u7740\u8d8a\u6765\u8d8a\u591a\u7684\u56fd\u5bb6\u5f00\u59cb\u5b9e\u65bd\u75ab\u82d7\u63a5\u79cd\u8ba1\u5212\uff0c\u52a0\u62ff\u5927\u536b\u751f\u90e8\u533b\u5b66\u79d1\u5b66\u5c40\u4e3b\u4efbMarc Berthiaume\u535a\u58eb\u8bf4\uff0c\u52a0\u62ff\u5927\u548c\u5176\u4ed6\u76d1\u7ba1\u673a\u6784\u6b63\u5728\u5171\u4eab\u6709\u5173\u63a5\u79cd\u75ab\u82d7\u8005\u62a5\u544a\u7684\u4efb\u4f55\u4e0d\u826f\u53cd\u5e94\u7684\u4fe1\u606f\u3002\u540c\u6837\uff0c\u5bf940,000\u540d\u4e09\u671f\u8bd5\u9a8c\u53c2\u4e0e\u8005\u7684\u5065\u5eb7\u72b6\u51b5\u7684\u76d1\u63a7\u4ecd\u5728\u7ee7\u7eed\u3002<\/p>\n

\u6839\u636e\u7f8e\u56fdFDA\u53d1\u5e03\u7684\u6570\u636e\uff0c\u53c2\u52a0\u8f89\u745e\u516c\u53f8\u4e09\u671f\u8bd5\u9a8c\u7684\u53c2\u4e0e\u8005\u62a5\u544a\u4e86\u4e00\u79cd\u8fc7\u654f\u53cd\u5e94\uff0c\u5c3d\u7ba1\u6709\u4eba\u5bf9\u75ab\u82d7\u6216\u8fd9\u79cd\u7279\u5b9a\u75ab\u82d7\u7684\u6210\u5206\u6709\u4e25\u91cd\u53cd\u5e94\u7684\u5386\u53f2\u88ab\u6392\u9664\u5728\u8be5\u5ba1\u5224\u4e4b\u5916\u3002<\/p>\n

12\u670812\u65e5\uff0c\u52a0\u62ff\u5927\u536b\u751f\u90e8\u53d1\u5e03\u4e86\u9488\u5bf9\u4e25\u91cd\u8fc7\u654f\u8005\u7684\u5b98\u65b9\u6307\u5357\u3002\u8054\u90a6\u653f\u5e9c\u8b66\u544a\u8bf4\uff0c\u52a0\u62ff\u5927\u7684\u6240\u6709\u75ab\u82d7\u201c\u90fd\u5bf9\u5305\u62ec\u8fc7\u654f\u53cd\u5e94\u5728\u5185\u7684\u4e25\u91cd\u8fc7\u654f\u53cd\u5e94\u7684\u98ce\u9669\u53d1\u51fa\u8b66\u544a\uff0c\u5e76\u4e14\u514d\u75ab\u8bca\u6240\u5df2\u914d\u5907\u4e86\u5e94\u5bf9\u8fd9\u4e9b\u7f55\u89c1\u4e8b\u4ef6\u7684\u88c5\u5907\uff0c\u201d\u8054\u90a6\u653f\u5e9c\u8b66\u544a\u8bf4\uff1a\u201c\u5bf9\u8f89\u745eCOVID-19\u75ab\u82d7\u4efb\u4f55\u6210\u5206\u8fc7\u654f\u8005\u4e0d\u8981\u63a5\u79cd\u3002\u201d<\/p>\n

\u52a0\u62ff\u5927\u536b\u751f\u90e8\u540c\u65f6\u5efa\u8bae\uff0c\u5982\u679c\u201c\u5bf9\u53e6\u4e00\u79cd\u75ab\u82d7\uff0c\u836f\u7269\u6216\u98df\u7269\u6709\u8fc7\u4e25\u91cd\u7684\u8fc7\u654f\u53cd\u5e94\uff0c\u5219\u5e94\u5728\u63a5\u79cd\u75ab\u82d7\u4e4b\u524d\u4e0e\u4e13\u4e1a\u4eba\u5458\u4ea4\u8c08\u3002\u201d<\/p>\n

\u4e0e\u5176\u4ed6\u75ab\u82d7\u4e00\u6837\uff0c\u8bb8\u591a16\u5c81\u53ca\u4ee5\u4e0a\u7684\u52a0\u62ff\u5927\u4eba\u5bf9\u8f89\u745e\u75ab\u82d7\u53ef\u80fd\u4f1a\u51fa\u73b0\u8f7b\u5ea6\u6216\u4e2d\u5ea6\u53cd\u5e94\uff0c\u8fd9\u610f\u5473\u7740\u4ed6\u4eec\u53ef\u4ee5\u5728\u514d\u75ab\u540e\u6301\u7eed\u6570\u5c0f\u65f6\u6216\u51e0\u5929\u3002\u4f46\u662f\uff0c\u5c31\u50cf\u4eba\u4eec\u83b7\u5f97\u5176\u4ed6\u75ab\u82d7\u4e00\u6837\uff0c\u5305\u62ec\u5b63\u8282\u6027\u6d41\u611f\u75ab\u82d7\uff0c\u4ed6\u4eec\u4e5f\u5fc5\u987b\u5728\u75ab\u82d7\u63a5\u79cd\u5904\u505c\u7559\u4e00\u4f1a\u513f\uff0c\u4ee5\u786e\u4fdd\u4ed6\u4eec\u6ca1\u6709\u66f4\u4e25\u91cd\u7684\u53cd\u5e94\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u95ee\uff1amRNA\u75ab\u82d7\u5bf9DNA\u6709\u4ec0\u4e48\u5f71\u54cd\uff1f\u5b83\u6539\u53d8DNA\u662f\u771f\u7684\u5417\uff1f<\/strong><\/p>\n

\u8f89\u745e-BioNTech\u548cModerna\u7814\u53d1\u7684mRNA\u75ab\u82d7\u4e0d\u6d89\u53caDNA\u3002RNA\u5c31\u50cf\u662fDNA\u7684\u4e34\u65f6\u5f71\u5370\u672c\uff0c\u7528\u4e8e\u5236\u9020\u86cb\u767d\u8d28\u3002\u86cb\u767d\u8d28\u662f\u7ec6\u80de\u7528\u6765\u751f\u957f\u548c\u4fee\u590d\u81ea\u8eab\u7684\u57fa\u7840\u3002\u4e00\u65e6\u86cb\u767d\u8d28\u88ab\u5236\u6210\uff0cRNA\u5c31\u88ab\u964d\u89e3\u3002<\/p>\n

\u9ea6\u514b\u9a6c\u65af\u7279\u5927\u5b66\u533b\u5b66\u526f\u6559\u6388\u3001\u5b89\u7701\u6c49\u5bc6\u5c14\u987f\u5e02\u7684\u4f20\u67d3\u75c5\u533b\u751fZain Chagla\u535a\u58eb\u8bf4\uff1a\u201c\u5bf9\u4eba\u7c7b\u800c\u8a00\uff0c\u8fc7\u7a0b\u603b\u662f\u4eceDNA\u5230RNA\u5230\u86cb\u767d\u8d28\u3002\u201d<\/p>\n

\u201c\u5728\u4eba\u7c7b\u7ec6\u80de\u4e2d\u4e0d\u80fd\u4eceRNA\u8f6c\u6362\u56deDNA\u3002\u8fd9\u662f\u4e0d\u53ef\u80fd\u7684\uff0c\u56e0\u4e3a\u6211\u4eec\u53ea\u662f\u6ca1\u6709\u5904\u7406\u5b83\u7684\u673a\u5236\u3002\u56e0\u6b64\uff0c\u4e0d\u5fc5\u62c5\u5fc3RNA\u75ab\u82d7\u4f1a\u4ee5\u67d0\u79cd\u65b9\u5f0f\u8fdb\u5165\u4eba\u7c7bDNA\u5e76\u6539\u53d8\u5b83\u3002\u201d<\/p>\n

\u4f46\u662f\uff0c\u6709\u4e00\u79cd\u53ef\u4ee5\u4eceRNA\u4ea7\u751fDNA\u7684\u5fae\u751f\u7269\uff0c\u9006\u8f6c\u5f55\u75c5\u6bd2\uff08retroviruses\uff09\uff0c\u5982HIV\u3002\u9ea6\u514b\u9a6c\u65af\u7279\u5927\u5b66\u4f20\u67d3\u75c5\u548c\u514d\u75ab\u5b66\u526f\u6559\u6388Matthew Miller\u8bf4\uff0c\u9006\u8f6c\u5f55\u75c5\u6bd2\u4ea7\u751f\u7684DNA\u6709\u65f6\u53ef\u4ee5\u6574\u5408\u5230\u7ec6\u80de\u4e2d\u3002<\/p>\n

\u8fd9\u5bfc\u81f4\u4e00\u4e9b\u7814\u7a76\u4eba\u5458\u63d0\u51fa\uff0c\u4ece\u7406\u8bba\u4e0a\u8bf4\uff0c\u9006\u8f6c\u5f55\u75c5\u6bd2\u611f\u67d3\u53ef\u80fd\u4f1a\u63d0\u4f9b\u6574\u5408mRNA\u6240\u9700\u7684\u86cb\u767d\u8d28\uff0c\u5c3d\u7ba1\u8fd9\u88ab\u8ba4\u4e3a\u201c\u6781\u4e0d\u53ef\u80fd\u201d\u3002<\/p>\n

Miller\u8bf4\uff0c\u9006\u8f6c\u5f55\u75c5\u6bd2\u7684RNA\u5728\u7ed3\u6784\u4e0a\u4e0emRNA\u4e0d\u540c\u3002\u201c\u56e0\u6b64\uff0c\u5373\u4f7f\u6709\u4eba\u611f\u67d3\u4e86\u9006\u8f6c\u5f55\u75c5\u6bd2\uff0c\u75ab\u82d7\u4e2d\u7684mRNA\u4e5f\u4e0d\u4f1a\u6539\u53d8\u6211\u4eec\u7684DNA\u3002\u201d<\/p>\n

\u66fc\u5c3c\u6258\u5df4\u5927\u5b66\u65b0\u5174\u75c5\u6bd2\u548c\u518d\u73b0\u75c5\u6bd2\u5206\u5b50\u53d1\u75c5\u673a\u7406\u7814\u7a76\u52a0\u62ff\u5927\u4e3b\u5e2dJason Kindrachuk\u4e5f\u8ba4\u4e3a\u6574\u5408\u7684\u98ce\u9669\u5f88\u5c0f\u3002<\/p>\n

\u4ed6\u6307\u51fa\uff0c\u75ab\u82d7\u4e2d\u7684mRNA\u542b\u91cf\u8fdc\u4f4e\u4e8e\u81ea\u7136\u611f\u67d3\u4ea7\u751f\u7684\u6570\u91cf\uff0c\u8fd9\u79cd\u7c7b\u578b\u7684COVID-19\u75ab\u82d7\u6216\u6b63\u5728\u7814\u53d1\u7528\u4e8e\u5176\u4ed6\u75be\u75c5\u7684mRNA\u75ab\u82d7\u7684\u8bd5\u9a8c\u5747\u672a\u663e\u793a\u51fa\u6574\u5408\u53ef\u80fd\u4f1a\u6709\u98ce\u9669\u7684\u8ff9\u8c61\u3002<\/p>\n

\u4ed6\u8865\u5145\u8bf4\uff0c\u5728\u4ea7\u54c1\u8bf4\u660e\u4e2d\uff0c\u6ca1\u6709\u9488\u5bf9HIV\u611f\u67d3\u8005\u7684\u7981\u5fcc\u75c7\uff0c\u5b83\u5bf9\u514d\u75ab\u529f\u80fd\u4f4e\u4e0b\u7684\u60a3\u8005\u552f\u4e00\u8bf4\u7684\u662f\u4ed6\u4eec\u7684\u514d\u75ab\u53cd\u5e94\u53ef\u80fd\u51cf\u5f31\u3002<\/p>\n

\u95ee\uff1a\u5982\u679c\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u53c2\u4e0e\u8005\u6ca1\u6709\u6545\u610f\u66b4\u9732\u4e8e\u75c5\u6bd2\uff0c\u90a3\u4e48\u75ab\u82d7\u836f\u6548\u662f\u5982\u4f55\u8ba1\u7b97\u7684\uff1f<\/strong><\/p>\n

\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u4eba\u5206\u4e3a\u4e24\u7ec4\uff0c\u63a5\u79cd\u75ab\u82d7\u7684\u4eba\u548c\u6ce8\u5c04\u5047\u75ab\u82d7\u7684\u4eba\u3002\u4ed6\u4eec\u4f1a\u50cf\u5f80\u5e38\u4e00\u6837\u53bb\u4e0a\u73ed\u548c\u4e0a\u5b66\uff0c\u5e76\u8fdb\u884c\u793e\u4ea4\u3002\u7531\u4e8e\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5927\u90e8\u5206\u662f\u5728\u5927\u6d41\u884c\u975e\u5e38\u6d3b\u8dc3\u7684\u5730\u65b9\u8fdb\u884c\uff0c\u5982\u7f8e\u56fd\u548c\u5df4\u897f\uff0c\u56e0\u6b64\u4e00\u5b9a\u6570\u91cf\u7684\u53c2\u4e0e\u8005\u5728\u65e5\u5e38\u751f\u6d3b\u4e2d\u4f1a\u63a5\u89e6\u5230COVID-19\u7684\u75c5\u6bd2\u3002<\/p>\n

\u901a\u8fc7\u6bd4\u8f83\u63a5\u79cd\u75ab\u82d7\u7684\u4eba\u548c\u63a5\u79cd\u5047\u75ab\u82d7\u7684\u4eba\u7684\u611f\u67d3\u6570\u6765\u8ba1\u7b97\u836f\u6548\u3002<\/p>\n

\u836f\u6548\uff08Efficacy\uff09\u662f\u8be5\u75ab\u82d7\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u6548\u679c\u5982\u4f55\u3002\u6709\u6548\u6027\uff08Effectiveness\uff09\u662f\u6307\u75ab\u82d7\u6216\u4ea7\u54c1\u5728\u73b0\u5b9e\u73af\u5883\u4e2d\u7684\u6548\u679c\u3002<\/p>\n

\u95ee\uff1a\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5982\u4f55\u89e3\u91ca\u75ab\u82d7\u7684\u201c 90\uff05\u836f\u6548\u201d\uff1f\u8fd9\u662f\u5426\u610f\u5473\u7740\u6bcf100\u4e2a\u4eba\u4e2d\u5c31\u670990\u4e2a\u4eba\u5bf9\u8be5\u75c5\u6bd2\u5177\u6709\u514d\u75ab\u529b\uff1f<\/p>\n

\u4e0d\u662f\u8fd9\u6837\u3002\u4e34\u5e8a\u8bd5\u9a8c\u5230\u76ee\u524d\u4e3a\u6b62\u901a\u5e38\u4e0d\u662f\u8bbe\u8ba1\u6765\u8861\u91cf\u4eba\u4eec\u662f\u5426\u5e78\u514d\u4e8e\u75c5\u6bd2\u3002\u5176\u76ee\u7684\u662f\u770b\u5b83\u662f\u5426\u51cf\u5c11\u4e86\u60a3\u4e0a\u75c7\u72b6\u6027\u75be\u75c5\u7684\u673a\u4f1a\u300290\uff05\u7684\u836f\u6548\u610f\u5473\u7740\uff0c\u63a5\u79cd\u75ab\u82d7\u7684\u4eba\u6bd4\u63a5\u79cd\u5047\u75ab\u82d7\u7684\u4eba\u51fa\u73b0\u75c7\u72b6\u6027COVID-19\u7684\u53ef\u80fd\u6027\u8981\u4f4e90\uff05\u3002<\/p>\n

\u4f46\u662f\uff0c\u8be5\u9879\u8bd5\u9a8c\u901a\u5e38\u672a\u6d4b\u8bd5\u65e0\u75c7\u72b6\u611f\u67d3\uff0c\u56e0\u6b64\u5c1a\u4e0d\u6e05\u695a\u5b9e\u9645\u4e0a\u6709\u591a\u5c11\u4eba\u5bf9\u611f\u67d3\u5177\u6709\u514d\u75ab\u529b\u3002<\/p>\n

\"\"<\/a> <\/p>\n

\u95ee\uff1a\u4ec0\u4e48\u6837\u7684\u5fd7\u613f\u8005\u53c2\u4e0e\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8c01\u88ab\u6392\u9664\u5728\u5916\uff1f\u4ece\u836f\u6548\u89d2\u5ea6\u6765\u770b\uff0c\u75ab\u82d7\u53ef\u4ee5\u4fdd\u62a4\u4e0d\u540c\u7684\u4eba\u5417\uff1f<\/strong><\/p>\n

\u8fc4\u4eca\u4e3a\u6b62\uff0c\u5927\u591a\u6570\u8bd5\u9a8c\u90fd\u5305\u62ec\u6210\u5e74\u4eba\u3002\u901a\u5e38\u8001\u5e74\u7fa4\u4f53\u75ab\u82d7\u7684\u6548\u679c\u8f83\u5dee\uff0c\u8fd9\u5c31\u662f\u4e3a\u4ec0\u4e48\u6709\u9488\u5bf9\u8001\u5e74\u4eba\u7684\u9ad8\u5242\u91cf\u6d41\u611f\u548c\u5e26\u72b6\u75b1\u75b9\u75ab\u82d7\u7684\u539f\u56e0\u3002<\/p>\n

\u8f89\u745eBioNTech\u548cModerna\u90fd\u8868\u793a\uff0c\u4ed6\u4eec\u7684\u75ab\u82d7\u7684\u836f\u6548\u5728\u5e74\u9f84\uff0c\u79cd\u65cf\u548c\u79cd\u65cf\u4ee5\u53ca\u6027\u522b\u4eba\u53e3\u7edf\u8ba1\u65b9\u9762\u5747\u4fdd\u6301\u4e00\u81f4\u3002\u8f89\u745e-BioNTech\u516c\u53f8\u8fd8\u6307\u51fa\uff0c\u8be5\u75ab\u82d7\u572865\u5c81\u4ee5\u4e0a\u7684\u6210\u5e74\u4eba\u4e2d\u6709\u6548\u7387\u4e3a94\uff05\u3002<\/p>\n

\u4e24\u5bb6\u516c\u53f8\u5747\u672a\u6709\u4e13\u95e8\u9488\u5bf9\u6162\u6027\u75c5\u60a3\u8005\u62a5\u544a\u7ed3\u679c\u3002<\/p>\n

\u9ea6\u514b\u9a6c\u65af\u7279\u5927\u5b66\u533b\u5b66\u526f\u6559\u6388Zain Chagla\u535a\u58eb\u8bf4\uff0c\u968f\u7740\u75ab\u82d7\u5728\u5168\u7403\u6570\u4ee5\u767e\u4e07\u8ba1\u7684\u4eba\u4e2d\u666e\u53ca\uff0c\u5c06\u4f1a\u66f4\u591a\u5730\u4e86\u89e3\u4e0d\u540c\u5e74\u9f84\u6bb5\u6216\u60a3\u6709\u5176\u4ed6\u75be\u75c5\u7684\u4eba\u3002<\/p>\n

Chagla\u8bf4\uff1a\u201c\u6211\u4eec\u5c06\u66f4\u597d\u5730\u4e86\u89e3\u8fd9\u79cd\u75ab\u82d7\u662f\u5426\u80fd\u963b\u6b62\u4eba\u4eec\u4f20\u64ad\u548c\u53bb\u9664COVID-19\uff0c\u6216\u8005\u53ea\u662f\u4f7f\u4ed6\u4eec\u7684\u75c7\u72b6\u597d\u8f6c\u800c\u4ecd\u7136\u53ef\u4ee5\u4f20\u64ad\u3002\u201d<\/p>\n

\u54c8\u5229\u6cd5\u514b\u65af\u513f\u7ae5\u4f20\u67d3\u75c5\u4e13\u5bb6Joanne Langley\u535a\u58eb\u662f\u52a0\u62ff\u5927\u75ab\u82d7\u5de5\u4f5c\u7ec4\u7684\u5171\u540c\u8d1f\u8d23\u4eba\uff0c\u4ed6\u8bf4\uff0c\u516c\u53f8\u6b63\u8ba1\u5212\u5728\u513f\u7ae5\u548c\u5b55\u5987\u4e2d\u8fdb\u884c\u8bd5\u9a8c\uff0c\u9884\u8ba1\u5c06\u57282021\u5e74\u5f00\u59cb\u3002\u75ab\u82d7\u751f\u4ea7\u5546\u8868\u793a\uff0c\u56fd\u9645\u8bd5\u9a8c\u4e5f\u6b63\u6269\u5c55\u5230\u5305\u62ec16\u5c81\u4ee5\u4e0b\u7684\u513f\u7ae5\u3002<\/p>\n

\u95ee\uff1a\u8f89\u745eBioNTech\u75ab\u82d7\u5bf9\u5b55\u5987\uff0c\u54fa\u4e73\u671f\u7684\u5987\u5973\u548c\u513f\u7ae5\u662f\u5426\u5b89\u5168\uff1f<\/strong><\/p>\n

\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u8fd8\u6ca1\u6709\u5173\u4e8e\u5b55\u5987\u548c\u54fa\u4e73\u671f\u5987\u5973\u7684\u4efb\u4f55\u5177\u4f53\u6570\u636e\uff0c\u56e0\u6b64\u75ab\u82d7\u751f\u4ea7\u5546\u4e0d\u80fd\u786e\u5b9a\u8be5\u75ab\u82d7\u5bf9\u4e8e\u8be5\u7c7b\u4eba\u7fa4\u662f\u5426\u5b89\u5168\u3002<\/p>\n

\u4f46\u662f\uff0c\u591a\u4f26\u591a\u4f20\u67d3\u75c5\u533b\u751fMichael Gardam\u535a\u58eb\u8bf4\uff1a\u201c\u8fd9\u79cd\u75ab\u82d7\u6ca1\u6709\u4efb\u4f55\u8ff9\u8c61\u8868\u660e\u5b83\u5c06\u5bf9\u5b55\u5987\u9020\u6210\u4efb\u4f55\u95ee\u9898\u3002\u201d\u5b55\u5987\u53ef\u80fd\u4f1a\u9009\u62e9\u63a5\u79cd\u75ab\u82d7\u3002\u4ed6\u5efa\u8bae\u4e0e\u4f60\u7684\u533b\u751f\u8ba8\u8bba\u3002<\/p>\n

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