(\u591a\u4f26\u591a26\u65e5\u52a0\u65b0\u793e\u7535)\u7814\u7a76\u4eba\u5458\u8bf4\uff0c\u897f\u67da\u548c\uff08Grapefruit\uff09\u897f\u67da\u6c41\u8574\u542b\u4e30\u5bcc\u7684\u7ef4\u4ed6\u547dC\uff0c\u4f46\u662f\u897f\u67da\u3001\u897f\u67da\u6c41\u6df7\u5408\u67d0\u4e9b\u5904\u65b9\u836f\u7269\uff0c\u53ef\u80fd\u5bf9\u4eba\u4f53\u6709\u5bb3\u3002<\/p>\n
\u6839\u636e\u5b89\u7701\u4f26\u6566\u897f\u5b89\u5927\u5b66(Western University)\u7684\u7efc\u5408\u7814\u7a76\uff0c\u897f\u67da\u6c41\u53ef\u4e0e\u8d85\u8fc785\u79cd\u53e3\u670d\u836f\u4ea7\u751f\u5316\u5b66\u4f5c\u7528\uff0c\u5176\u4e2d\u7ea6\u6709\u534a\u6570\u53ef\u80fd\u9020\u6210\u4e25\u91cd\u540e\u679c\uff0c\u751a\u81f3\u6709\u81f4\u547d\u4e4b\u865e\u3002<\/p>\n
\u62a5\u544a\u4f5c\u8005\u8bf4\uff1a\u201c\u4e0d\u5c11\u836f\u7269\u4e0e\u897f\u67da\u4ea7\u751f\u5316\u5b66\u4f5c\u7528\uff0c\u90a3\u4e9b\u836f\u7269\u662f\u5e7f\u6cdb\u4f7f\u7528\u7684\u5904\u65b9\u836f\uff0c\u662f\u6cbb\u7406\u4e00\u4e9b\u91cd\u8981\u3001\u666e\u904d\u75be\u75c5\u7684\u57fa\u672c\u836f\u7269\u3002\u201d<\/p>\n
\u4ed6\u4eec\u7684\u7814\u7a76\u5728\u5468\u4e00\u7248\u300a\u52a0\u62ff\u5927\u533b\u5b66\u534f\u4f1a\u671f\u520a\u300b(Canadian Medical Association Journal)\u53d1\u8868\uff0c\u4e3b\u8981\u7814\u7a76\u5458\u8d1d\u5229(David Bailey)\u662f\u52b3\u68ee\u5065\u5eb7\u7814\u7a76\u9662(Lawson Health Research Institute)\u4e34\ue27c\u836f\u7269\u5b66\u5bb6\u3002<\/p>\n
\u4ed6\u8bf4\uff0c\u5728\u8fc7\u53bb4\u5e74\u95f4\uff0c\u53ef\u80fd\u4e0e\u897f\u67da\u4ea7\u751f\u5316\u5b66\u4f5c\u7528\u3001\u5f15\u53d1\u4e25\u91cd\u526f\u4f5c\u7528\u7684\u836f\u7269\uff0c\u4ece17\u79cd\u589e\u52a0\u5230\u6700\u5c1143\u79cd\u3002<\/p>\n
\u8d1d\u5229\u5728\u5b89\u7701\u4f26\u6566\u8bf4\uff1a\u201c\u5176\u4e2d\u4e00\u534a\u836f\u7269\u5176\u5b9e\u6709\u5ffd\u7136\u593a\u547d\u7684\u53ef\u80fd\u3002\u201d<\/p>\n
\u4ed6\u6307\u51fa\uff0c\u897f\u67da\u4e0e\u67d0\u4e9b\u5904\u65b9\u836f\u7269\u6df7\u5408\u670d\u7528\uff0c\u4ea7\u751f\u5316\u5b66\u4f5c\u7528\uff0c\u53ef\u80fd\u9020\u6210\u6025\u6027\u80be\u810f\u3001\u547c\u5438\u7cfb\u7edf\u8870\u7aed\uff1b\u80a0\u80c3\u51fa\u8840\uff0c\u6216\u662f\u5176\u4ed6\u4e25\u91cd\u6548\u5e94\u3002<\/p>\n
\u897f\u67da\u5f71\u54cd\u7684\u5904\u65b9\u836f\u7269\u5305\u62ec\u964d\u4f4e\u80c6\u56fa\u9187\u7684\u4ed6\u6c40\u7c7b\u836f\u7269\uff0c\u4e00\u4e9b\u5173\u952e\u7684\u5fc3\u810f\u836f\uff0c\u67d0\u4e9b\u6291\u5236\u7cbe\u795e\u75c5\u7684\u836f\u7269\u3001\u89e3\u75db\u5242\u3002<\/p>\n
\u897f\u67da\u7684\u4e00\u79cd\u5316\u5b66\u6210\u5206\uff0c\u4e0e\u63a7\u5236\u80a0\u80c3\u5982\u4f55\u5438\u6536\u836f\u7269\u7684\u4e00\u79cd\ueceb\u4ea7\u751f\u4f5c\u7528\uff0c\u589e\u5f3a\u836f\u529b\uff0c\u5242\u91cf\u5bf9\u8eab\u4f53\u6709\u5bb3\u3002<\/p>\n
\u5176\u4ed6\u67d1\u6854\u7c7b\u542b\u6709\u540c\u7c7b\u5316\u5b66\u6210\u5206\uff0c\u6216\u6709\u4e00\u70b9\u542b\u91cf\uff0c\u5305\u62ec\u897f\u67e0\u3001\u67da\u5b50\u4e0e\u5e38\u7528\u4e8e\u6854\u5b50\u9171\u7684\u585e\u7ef4\u5229\u4e9a\u6a59(Seville orange)\u3002<\/p>\n
\u5e38\u7528\u7684\u4ed6\u6c40\u7c7b\u5904\u65b9\u836f\uff0c\u5982\u963f\u6258\u4f10\u4ed6\u6c40(atorvastatin, Lipitor)\u3001\u8f9b\u4f10\u4ed6\u6c40(simvastatin, Zocor)\u4e0e\u6d1b\u4f10\u4ed6\u6c40(lovastatin, Mevacor, Altoprev)\uff0c\u6709\u9ad8\u81f3\u5f88\u5927\u98ce\u9669\uff0c\u4e0e\u897f\u67da\u4ea7\u751f\u5316\u5b66\u4f5c\u7528\uff0c\u5f15\u53d1\u6a2a\u7eb9\u808c\u6eb6\u89e3\u75c7(rhabdomyolysis)\uff0c\u90a3\u662f\u808c\u8089\u7ea4\u7ef4\u5931\u5e38\uff0c\u53ef\u5bfc\u81f4\u6025\u6027\u80be\u8870\u7aed\u3002\u8d1d\u5229\u79f0\uff0c\u75c5\u4eba\u670d\u8584\u8840\u4e38\u4fdd\u6813\u901a(Plavix)\uff0c\u9632\u6b62\u5fc3\u810f\u75c5\u548c\u4e2d\u98ce\uff0c\u8fd9\u79cd\u836f\u5b8c\u5168\u4e0d\u80fd\u4e0e\u897f\u67da\u6df7\u5408\u3002<\/p>\n
\u98df\u7528\u897f\u67da\u52ff\u6df7\u548c\u836f\u7269\u6291\u5236\u5fc5\u8981\u9175\u7d20 \u4e25\u91cd\u53ef\u81f4\u547d<\/strong><\/p>\n \u661f\u5c9b\u65e5\u62a5\/\u65b0\u8fd1\u7684\u4e00\u9879\u533b\u5b66\u7814\u7a76\u8b66\u544a\uff0c\u897f\u67da\u4e0e\u4e0d\u5c11\u836f\u7269\u6df7\u5408\u540e\u4f1a\u4ea7\u751f\u4e25\u91cd\u6548\u679c\uff0c\u8db3\u4ee5\u81f4\u547d\uff0c\u7279\u522b\u662f\u5bf9\u5e74\u8fc745\u5c81\u4eba\u58eb\u3002\u6709\u5173\u836f\u7269\u6570\u76ee\u5e76\u6108\u6765\u6108\u591a\u3002<\/p>\n \u8be5\u7814\u7a76\u520b\u8f7d\u4e8e\u300a\u52a0\u62ff\u5927\u533b\u5b66\u4f1a\u671f\u520a\u300b\uff08Canadian Medical Association Journal, CMAJ\uff09\u3002\u5e26\u9886\u7814\u7a76\u7684Dr. David Bailey\u533b\u751f\u6307\u51fa\uff0c\u4e0d\u5c11\u65b0\u63a8\u51fa\u5e02\u9762\u7684\u836f\u7269\u4e0e\u897f\u67da\u6df7\u5408\u540e\u53ef\u4ea7\u751f\u975e\u5e38\u4e25\u91cd\u7684\u526f\u4f5c\u7528\uff0c\u5bf9\u514d\u75ab\u7cfb\u7edf\u53d7\u635f\u53ca\u80be\u5e26\u6bd2\u4eba\u58eb\u5e26\u6765\u6025\u6027\u80be\u8870\u7aed\u3001\u547c\u5438\u529f\u80fd\u8870\u7aed\u3001\u6d88\u5316\u9053\u51fa\u8840\u3001\u9aa8\u9ad3\u6291\u5236\uff0c\u4e25\u91cd\u8005\u751a\u81f3\u4f1a\u56e0\u5fc3\u5f8b\u5931\u5e38\u800c\u7a81\u7136\u6b7b\u4ea1\u3002<\/p>\n \u8be5\u7814\u7a76\u56e2\u961f\u65e9\u4e8e20\u5e74\u524d\uff0c\u53d1\u73b0\u897f\u67da\u6c41\u4e0e\u4e00\u4e9b\u836f\u7269\u4e4b\u95f4\u4ea7\u751f\u7684\u526f\u4f5c\u7528\uff0c\u5e76\u66fe\u4e8e\u8457\u540d\u533b\u5b66\u671f\u520b\u53d1\u8868\u7814\u7a76\u7ed3\u679c\u3002\u4ed6\u4eec\u4e8e\u56db\u5e74\u524d\u53ea\u53d1\u73b0\u670917\u79cd\u836f\u7269\u53ef\u80fd\u5bfc\u81f4\u4e25\u91cd\u5065\u5eb7\u95ee\u9898\uff0c\u4f46\u73b0\u5728\u6709\u5173\u836f\u7269\u6570\u76ee\u5df2\u589e\u52a0\u81f344\u79cd\uff0c\u5305\u62ec\u4e00\u4e9b\u7528\u4ee5\u6cbb\u7597\u5e38\u89c1\u91cd\u75c5\u7684\u591a\u79cd\u53e3\u670d\u836f\u7269\uff0c\u5176\u4e2d\u6709Crizotinib\u53caPazopanib\u7b49\u6297\u764c\u836f \u3001Erythromycin\u53caQuinine\u7b49\u6297\u751f\u7d20\uff0c\u4ee5\u53caApixaban\u53caFelodipine\u7b49\u6297\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u7684\u5e38\u7528\u836f\u7269\u3002<\/p>\n \u6613\u9020\u6210\u201c\u8fc7\u91cf\u7528\u836f\u201d<\/p>\n \u7814\u7a76\u6307\u51fa\uff0c\u5e74\u8fc745\u5c81\u4eba\u58eb\u4e3a\u6700\u9ad8\u5371\u4e00\u65cf\uff0c\u539f\u56e0\u662f\u4ed6\u4eec\u6700\u591a\u996e\u7528\u897f\u67da\u6c41\u53ca\u8f83\u591a\u670d\u7528\u836f\u7269\u3002\u897f\u67da\u6c41\u542b\u6709\u6291\u5236\u6d88\u5316\u7cfb\u7edf\u5fc5\u8981\u9175\u7d20\u7684\u5316\u5408\u7269\u8d28furanocoumarins\uff0c\u800c\u6709\u5173\u9175\u7d20\u53ef\u51cf\u5c11\u8840\u6db2\u5438\u6536\u836f\u7269\uff0c\u4ee4\u836f\u7269\u5931\u53bb\u516b\u81f3\u4e5d\u6210\u7684\u6548\u679c\uff0c\u56e0\u6b64\u5927\u90e8\u5206\u836f\u7269\u5242\u91cf\u5747\u56e0\u6b64\u800c\u201c\u52a0\u91cd\u201d\u3002\u4f46\u4e00\u65e6\u8be5\u9175\u7d20\u529f\u80fd\u88ab\u897f\u67da\u6291\u5236\uff0c\u5219\u4f1a\u9020\u6210\u201c\u8fc7\u91cf\u7528\u836f\u201d\uff0c\u6c34\u5e73\u8fdc\u8d85\u539f\u5148\u6570\u500d\u3002<\/p>\n \u6b64\u5916\uff0c\u5176\u4ed6\u751f\u679c\u5982\u9178\u6a59\u548c\u67da\u5b50\u4ea6\u542b\u6709furanocoumarins\uff0c\u7814\u7a76\u63a8\u65ad\u4ea6\u6709\u53ef\u80fd\u4ea7\u751f\u76f8\u540c\u526f\u4f5c\u7528\u3002<\/p>\n \u8d44\u6599\u6765\u6e90\uff1a\u661f\u62a5<\/p>\n ——<\/p>\n 20121129\/4\u79cd\u98df\u7269\u53ca\u996e\u6599\u4e0e\u836f\u7269\u76f8\u514b<\/strong><\/p>\n \u660e\u62a5\/\u52a0\u62ff\u5927\u533b\u751f\u7ed9\u75c5\u4eba\u533b\u5631\uff0c\u5c0f\u5fc3\u98df\u7528\u897f\u67da\uff0c\u56e0\u4e3a\u8fd1\u5e74\u6709\u66f4\u591a\u836f\u7269\u4e0e\u897f\u67da\u76f8\u514b\uff0c\u53ef\u80fd\u5f15\u8d77\u4e25\u91cd\u526f\u4f5c\u7528\u3002\u5176\u5b9e\uff0c\u4e0e\u5e38\u7528\u836f\u7269\u76f8\u514b\u7684\u98df\u7269\u548c\u996e\u6599\u8fd8\u67094\u79cd\uff0c\u4eba\u4eec\u8981\u7559\u610f\u3002<\/p>\n \u4ece\u964d\u80c6\u56fa\u9187\u836f\u5230\u7a00\u8840\u5242\uff0c\u5f88\u591a\u836f\u7269\u4e0e\u5e73\u5e38\u65e0\u5bb3\u7684\u98df\u7269\u6df7\u5408\uff0c\u5c31\u4f1a\u4ea7\u751f\u5316\u5b66\u4f5c\u7528\uff0c\u5f15\u8d77\u4e0d\u826f\u526f\u4f5c\u7528\u3002\u4eba\u4eec\u5e94\u8be5\u7ec6\u8bfb\u5904\u65b9\u836f\u6807\u7b7e\uff0c\u5411\u533b\u751f\u6216\u836f\u5242\u5e08\u67e5\u8be2\uff0c\u5728\u670d\u7528\u7279\u5b9a\u836f\u7269\u671f\u95f4\u5e94\u5426\u6212\u53e3\u3002<\/p>\n \u82f1\u56fd\u7684\u56fd\u5bb6\u533b\u7597\u7814\u7a76\u6240\u6307\u51fa\uff0c\u7ef4\u4ed6\u547dK\u4e30\u5bcc\u7684\u98df\u7269\u4f1a\u51cf\u5f31\u8584\u8840\u4e38\u534e\u6cd5\u6797(warfarin)\u7684\u836f\u6548\u3002\u534e\u6cd5\u6797\u662f\u5e38\u7528\u5904\u65b9\u836f\uff0c\u591a\u4f26\u591a\u5927\u5b66\u836f\u7269\u5b89\u5168\u4e13\u5bb6\u6731\u5c14\u6797\u514b\u533b\u751f(David Juurlink)\u4f30\u8ba1\uff0c\u5149\u662f\u5b89\u7701\uff0c\u5c31\u670910\u4e07\u4eba\u670d\u7528\u8fd9\u79cd\u8584\u8840\u836f\u3002<\/p>\n \u7ef4\u4ed6\u547dK\u4e30\u5bcc\u7684\u98df\u7269\u5305\u62ec\u9999\u8349\uff0c\u4f8b\u5982\u897f\u6d0b\u9999\u83dc(parsley)\u53ca\u82ab\u837d(coriander)\u3001\u7eff\u53f6\u83dc\u5982\u83e0\u83dc\u3001\u745e\u58eb\u751c\u83dc(Swiss chard)\uff0c\u8fd8\u6709\u9ec4\u8c46\u3001\u9e70\u5634\u8c46(chickpea)\u3001\u5207\u8fbe\u4e73\u916a\u548c\u7eff\u8336\u3002<\/p>\n \u4eba\u4eec\u8fdb\u98df\u5927\u91cf\u9ed1\u7518\u8349(black licorice)\uff0c\u540c\u65f6\u670d\u7528\u62c9\u8bfa\u8f9b(Lanoxin)\uff0c\u4ea7\u751f\u6bd2\u7d20\u7684\u673a\u4f1a\u66f4\u5927\u3002\u62c9\u8bfa\u8f9b\u6cbb\u4e3b\u6cbb\u5145\u8840\u6027\u5fc3\u810f\u8870\u7aed\u4e0e\u5fc3\u5f8b\u4e0d\u6574\uff0c\u7f8e\u56fd\u98df\u7269\u53ca\u836f\u7269\u7ba1\u7406\u5c40(U.S. Food and Drug Administration)\u8bf4\uff0c\u62c9\u8bfa\u8f9b\u4e5f\u53ef\u80fd\u964d\u4f4e\u67d0\u4e9b\u964d\u8840\u538b\u836f\u7269\u548c\u5229\u5c3f\u5242\u7684\u836f\u6548\u3002<\/p>\n \u6731\u5c14\u6797\u514b\u8bf4\uff0c\u5976\u7c7b\u548c\u8865\u5145\u5242\u7684\u9499\u8d28\u90fd\u4f1a\u5f71\u54cd\u4eba\u4f53\u5438\u6536\u7532\u72b6\u817a\u836f\u7269\u3001\u6297\u751f\u7d20\u5982\u6297\u751f\u7d20\u73af\u4e19\u6c99\u661f(ciprofloxacin)\u4e0e\u5de6\u6c27\u6c1f\u6c99\u661f(levofloxacin)\u7684\u80fd\u529b\u3002<\/p>\n \u9152\u7cbe\u9020\u6210\u4f24\u5bb3\u6700\u5927<\/p>\n \u8fd8\u6709\u9152\u7cbe\uff0c\u8bb8\u591a\u79cd\u836f\u7269\u8ddf\u9152\u7cbe\u76f8\u514b\uff0c\u5305\u62ec\u8584\u8840\u4e38\u6cd5\u534e\u6797\u3001\u6297\u751f\u7d20\u3001\u6297\u6291\u90c1\u836f\u3001\u7cd6\u5c3f\u75c5\u836f\u7269\u3001\u7cbe\u795e\u75c5\u836f\u7269\u5982Thorazine\u548c\u6297\u766b\u75eb\u836f\u7269\u3002<\/p>\n \u963f\u5c14\u4f2f\u8fbe\u7701\u533b\u7597\u670d\u52a1\u5c40(Alberta Health Services)\u6307\u51fa\uff0c\u4e0d\u540c\u7684\u836f\u7269\u4e0e\u9152\u7cbe\u6df7\u5408\uff0c\u53ef\u80fd\u4ea7\u751f\u4e0d\u540c\u7684\u53cd\u5e94\uff0c\u4f8b\u5982\u7cd6\u5c3f\u75c5\u836f\u7269\u6df7\u5408\u9152\u7cbe\uff0c\u75c5\u4eba\u53ef\u80fd\u6709\u6076\u5fc3\u548c\u5934\u75db\u7684\u53cd\u5e94\u3002<\/p>\n \u6731\u5c14\u6797\u514b\u6307\u51fa\uff0c\u98df\u7269\u4e0e\u836f\u7269\u76f8\u514b\uff0c\u9152\u7cbe\u9020\u6210\u7684\u4f24\u5bb3\u6700\u5927\u3002<\/p>\n","protected":false},"excerpt":{"rendered":" (\u591a\u4f26\u591a26\u65e5\u52a0\u65b0\u793e\u7535)\u7814\u7a76\u4eba\u5458\u8bf4\uff0c\u897f\u67da\u548c\uff08Grapefruit\uff09\u897f\u67da\u6c41\u8574\u542b\u4e30\u5bcc\u7684\u7ef4\u4ed6\u547dC\uff0c\u4f46\u662f\u897f\u67da\u3001\u897f\u67da\u6c41\u6df7\u5408\u67d0\u4e9b\u5904\u65b9\u836f\u7269\uff0c\u53ef\u80fd\u5bf9\u4eba\u4f53\u6709\u5bb3\u3002 \u6839\u636e\u5b89\u7701\u4f26\u6566\u897f\u5b89\u5927\u5b66(Western University)\u7684\u7efc\u5408\u7814\u7a76\uff0c\u897f\u67da\u6c41\u53ef\u4e0e\u8d85\u8fc785\u79cd\u53e3\u670d\u836f\u4ea7\u751f\u5316\u5b66\u4f5c\u7528\uff0c\u5176\u4e2d\u7ea6\u6709\u534a\u6570\u53ef\u80fd\u9020\u6210\u4e25\u91cd\u540e\u679c\uff0c\u751a\u81f3\u6709\u81f4\u547d\u4e4b\u865e…
Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[],"_links":{"self":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts\/37756"}],"collection":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=37756"}],"version-history":[{"count":2,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts\/37756\/revisions"}],"predecessor-version":[{"id":37863,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=\/wp\/v2\/posts\/37756\/revisions\/37863"}],"wp:attachment":[{"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=37756"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=37756"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.jackjia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=37756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}